研究成果

論文發表    國內外會議    獲獎與專利

2022

  • Po-Kang Lin, Yu-Hsien Chiu+, Chiu-Jung Huang+, Chien-Yao Wang, Mei-Lien Pan, Da-Wei Wang, Hong-Yuan Mark Liao, Yong-Sheng Chen, Chieh-Hsiung Kuan, Shih-Yen Lin*, Li-Fen Chen* (2022). PADAr: physician-oriented artificial intelligence-facilitating diagnosis aid for retinal diseases. Journal of Medical Imaging, 9(4) 044501.
  • Li-Kai Cheng, Yu-Hsien Chiu, Ying-Chia Lin, Wei-Chi Li, Tzu-Yi Hong, Ching-Ju Yang, Chung-Heng Shih, Tzu-Chen Yeh, Wen-Yih Isaac Tseng, Hsin-Yen Yu, Jen-Chuen Hsieh*, Li-Fen Chen* (2022). Long-term vocal training induces white matter plasticity in emotion and language networks. Human Brain Mapping. https://doi.org/10.1002/hbm.26054.
  • Pei-Chun Chang, Yan-Yu Tien, Chia-Lin Chen, Li-Fen Chen, Yong-Sheng Chen, Hui-Ling Chan (2022). Facial Image Reconstruction from Functional Magnetic Resonance Imaging via GAN Inversion with Improved Attribute Consistency. 2022 International Joint Conference on Neural Networks (IJCNN), 2022, p.1054-8

2021

  • Meng-Tien Hsieh, Hsin-Jie Lu, Li-Fen Chen, Chia-Yih Liu, Shih-Chieh Hsu, Chia-Hsiung Cheng* (2021). Cancellation but not restraint ability is modulated by trait anxiety: An event-related potential and oscillation study using Go-NoGo and stop-signal tasks. Journal of Affective Disorders, 299, 188–195.
  • Wei-Yang Yu+, Intan Low+, Chien Chen, Jong-Ling Fuh*, Li-Fen Chen* (2021). Brain dynamics altered by photic stimulation in in patients with Alzheimer’s disease and mild cognitive impairment. Entropy, 23(4):427.
  • Hui-Ling Chan+*, Intan Low+, Li-Fen Chen, Yong-Sheng Chen, Jen-Chuen Hsieh* (2021). A novel beamformer-based imaging of phase-amplitude coupling (BIPAC) unveiling the inter-regional connectivity of emotional prosody processing in women with primary dysmenorrhea. Journal of Neural Engineering, 18:046074.
  • Tun-Wei Hsu, Jong-Ling Fuh*, Da-Wei Wang, Li-Fen Chen, Chia-Jung Chang, Wen-Sheng Huang, Hsiu-Mei Wu*, Wan-Yuo Guo (2021). Disrupted brain connectivity pathways with different stages of dementia from FDG-PET brain persistent homology network. Scientific Reports 11, 5396.
  • Wei-Chi Li, Hsiang-Tai Chao, Ming-Wei Lin, Horng-Der Shen, Li-Fen Chen*, Jen-Chuen Hsieh* (2021). Neuroprotective effect of Val variant of BDNF Val66Met polymorphism on hippocampus is modulated by the severity of menstrual pain. NeuroImage: Clinical, 102576.

 

2020

  • Chih-Ping Chung+, Jiun-Wei Chen+, Feng-Chi Chang, Wei-Chi Li, Yi-Chung Lee, Li-Fen Chen*, and Yi-Chu Liao* (2020). Cerebral microbleed burdens in specific brain regions are associated with disease severity of CADASIL. Journal of the American Heart Association, e016233.

 

2018

  • Intan Low, Po-Chih Kuo, Cheng-Lin Tsai, Yu-Hsiang Liu, Ming-Wei Lin, Hsiang-Tai Chao, Yong-Sheng Chen, Jen-Chuen Hsieh*, Li-Fen Chen* (2018). Interactions of BDNF Val66Met polymorphism and menstrual pain on brain complexity. Frontiers in Neuroscience 12:826.
  • Intan Low, Shyh-Yuh Wei, Pin-Shiuan Lee, Wei-Chi Li, Lin-Chien Lee, Jen-Chuen Hsieh*, Li-Fen Chen* (2018) Neuroimaging Studies of Primary Dysmenorrhea. In: Shyu BC., Tominaga M. (eds) Advances in Pain Research: Mechanisms and Modulation of Chronic Pain. Advances in Experimental Medicine and Biology, vol 1099. 179-199. Springer, Singapore ISBN 978-981-13-1756-9
  • Lin-Chien Lee, Yueh-Hua Chen, Chia-Shu Lin, Wei-Chi Li, Intan Low, Cheng-Hao Tu, Chih-Che Chou, Chou-Ming Cheng, Tzu-Chen Yeh, Li-Fen Chen, Hsiang-Tai Chao, Jen-Chuen Hsieh* (2018). Unaltered intrinsic functional brain architecture in young women with primary dysmenorrhea. Scientific Reports 8(1):12971.
  • Chih-Che Chou, Wei-Chung Mao, Chiu-Jung Huang, Cheng-Ta Li, Tung-Ping Su, Chin-Bin Yeh, San-Yuan Huang, Fa-Hsuan Lin, Li-Fen Chen*, Jen-Chuen Hsieh* (2018). Deficient Emotional Intelligence and Dysfunctional Early Emotional Prosody Processing Varying with the Severity of Auditory Hallucinations in Schizophrenics. Neuropsychiatry (London). 8(4):1297-1309.
  • Po-Chih Kuo, Yong-Sheng Chen*, Li-Fen Chen* (2018). Manifold decoding for neural representations of face viewpoint and gaze direction using magnetoencephalographic data. Human Brain Mapping. 39(5):2191-2209. doi: 10.1002/hbm.23998.

2017

  • Intan Low, Po-Chih Kuo, Yu-Hsiang Liu, Cheng-Lin Tsai, Hsiang-Tai Chao, Jen-Chuen Hsieh, Li-Fen Chen*, Yong-Sheng Chen* (2017). Altered brain complexity in women with primary dysmenorrhea: a resting-state MEG study using multiscale entropy analysis. Entropy, 19(12):680.
  • Pin-Shiuan Lee, Intan Low, Yong-Sheng Chen, Cheng-Hao Tu, Hsiang-Tai Chao, Jen-Chuen Hsieh*Li-Fen Chen* (2017). Encoding of menstrual pain experience with theta oscillations in women with primary dysmenorrhea. Scientific Reports 7:15977.
  • Shyh-Yuh Wei, Li-Fen Chen, Ming-Wei Lin, Wei-Chi Li, Intan Low, Ching-Ju Yang, Hsiang-Tai Chao, Jen-Chuen Hsieh* (2017). The OPRM1 A118G polymorphism modulates the descending pain modulatory system for individual pain experience in young women with primary dysmenorrhea. Scientific Reports, 7:39906.
  • Po-Chih Kuo, Yi-Ti Chen, Yong-Sheng Chen*, Li-Fen Chen (2017). Decoding the perception of endogenous pain from resting-state MEG. NeuroImage, 144:1–11.

2016

  • Wei-Chung Mao, Li-Fen Chen*, Chia-Hsing Chi, Ching-Hung Lin, Yu-Chen Kao, Wen-Yau Hsu, Hsien-Yuan Lan, Jen-Chuen Hsieh* (2016). Traditional Chinese version of the Mayer Salovey Caruso Emotional Intelligence Test (MSCEIT-TC): Its validation and application to schizophrenic individuals. Psychiatry Research, 243(30):61-70.
  • Ting-Hsuan Wu, Cheng-Hao Tu, Hsiang-Tai Chao, Wei-Chi Li, Intan Low, Chih-Ying Chuang, Tzu-Chen Yeh, Chou-Ming Cheng, Chih-Che Chou, Li-Fen Chen*, Jen-Chuen Hsieh* (2016). Dynamic changes of functional pain connectome in women with primary dysmenorrhea. Scientific Reports, 24(6): 24543.
  • Shyh-Yuh Wei, Hsiang-Tai Chao, Cheng-Hao Tu, Ming-Wei Lin, Wei-Chi Li, Intan Low, Horng-Der Shen, Li-Fen Chen*, Jen-Chuen Hsieh* (2016). The BDNF Val66Met polymorphism is associated with the functional connectivity dynamics of pain modulatory systems in primary dysmenorrhea. Scientific Reports, 24(6): 23639.
  • Shyh-Yuh Wei, Hsiang-Tai Chao, Cheng-Hao Tu, Wei-Chi Li, Intan Low, Chih-Ying Chuang, Li-Fen Chen, Jen-Chuen Hsieh* (2016). Changes in functional connectivity of pain modulatory systems in women with primary dysmenorrhea. Pain, 157:92–102.

2015

  • Po-Chih Kuo, Yong-Sheng Chen*, Li-Fen Chen (2015). Supervised learning for neural manifold using spatiotemporal brain activity. Journal of Neural Engineering, 12(6):066025 (12pp).
  • Hui-Ling Chan, Li-Fen Chen, I-Tzu Chen, Yong-Sheng Chen* (2015). Beamformer-based spatiotemporal imaging of linearly-related source components using electromagnetic neural signals. NeuroImage, 114:1-17.
  • Tai-Ying Liu, Yong-Sheng Chen, Jen-Chuen Hsieh, Li-Fen Chen* (2015). Asymmetric engagement of amygdala and its gamma connectivity in early emotional face processing. PLoS ONE 10(1):e0115677.
  • Wei-Chi Li, Cheng-Hao Tu, Hsiang-Tai Chao, Tzu-Chen Yeh, Li-Fen Chen, Jen-Chuen Hsieh* (2015). High prevalence of incidental brain findings in primary dysmenorrhea. European Journal of Pain 19(8):1071-4.

2014

  • Lin-Chien Lee, Cheng-Hao Tu, Li-Fen Chen, Horng-Der Shen, Hsiang-Tai Chao, Ming-Wei Lin*, Jen-Chuen Hsieh* (2014). Association of brain-derived neurotrophic factor gene Val66Met polymorphism with primary dysmenorrhea. PLoS ONE 9(11): e112766. doi:10.1371/journal.pone.0112766.
  • Po-Chih Kuo, Yong-Sheng Chen*, Li-Fen Chen*, Jen-Chuen Hsieh (2014). Decoding and encoding of visual patterns using magnetoencephalographic data represented in manifolds. NeuroImage 102:435-450.
  • Cheng-Ta Li*, Mu-Hong Chen, Chi-Hung Juan, Hsiang-Hsuan Huang, Li-Fen Chen, Jen-Chuen Hsieh, Pei-Chi Tu, Ya-Mei Bai, Shin-Jen Tsai, Ying-Chiao Lee, Tung-Ping Su* (2014). Efficacy of prefrontal theta-burst stimulation in refractory depression: a randomized sham-controlled study. Brain 137(7):2088-98.
  • Tai-Ying Liu, Yong-Sheng Chen, Tung-Ping Su, Jen-Chuen Hsieh*, Li-Fen Chen* (2014). Abnormal early gamma responses to emotional faces differentiate unipolar from bipolar disorder patients. BioMed Research International. 2014:906104.

2013

  • Cheng-Ta Li, Li-Fen Chen, Pei-Chi Tu, Shyh-Jen Wang, Mu-Hong Chen, Tung-Ping Su, Jen-Chuen Hsieh* (2013). Impaired prefronto-thalamic functional connectivity as a key feature of treatment-resistant depression: a combined MEG, PET and rTMS study. PLoS ONE 8(8): e70089.

2012

  • Hsiao-Ping Shen, Yong-Sheng Chen, Jen-Chuen Hsieh, Tung-Ping Su, and Li-Fen Chen* (2012). Abnormal neural responses to facial expression images in major depressive patients. Journal of Neuroscience and Neuroengineering, 1(1): 90-96.
  • Hui-Ling Chan, Yong-Sheng Chen*, and Li-Fen Chen (2012). Selection of independent components based on cortical mapping of electromagnetic activity. Journal of Neural Engineering, 9(5):056006.
  • Peichi Tu, Li-Fen Chen, Jen-Chuen Hsieh, Ya-Mei Bai, Cheng-Ta Li, and Tung-Ping Su*. (2012). Regional cortical thinning in patients with major depressive disorder: a surface-based morphometry study. Psychiatry Res, 202(3):206-13.
  • Tai-Ying Liu, Jen-Chuen Hsieh, Yong-Sheng Chen, Pei-Chi Tu, Tung-Ping Su*, and Li-Fen Chen* (2012) Different patterns of abnormal gamma oscillatory activity in unipolar and bipolar disorder patients during an implicit emotion task. Neuropsychologia, 50:1514–1520.

2010

  • Jia-Xiu Liu, Yong-Sheng Chen, Jen-Chuen Hsieh, Tung-Ping Su, Tzu-Chen Yeh, and Li-Fen Chen* (2010) Differences in white matter abnormalities between bipolar I and II disorders. Journal of Affective Disorders, 127:309–315.
  • Cheng-Hao Tu, David M. Niddam, Hsiang-Tai Chao, Li-Fen Chen, Yong-Sheng Chen, Yu-Te Wu, Tzu-Chen Yeh, Jiing-Feng Lirng, and Jen-Chuen Hsieh* (2010) Brain morphological changes associated with cyclic menstrual pain. Pain, 150(3):462–468.
  • Pin-Shiuan Lee, Yong-Sheng Chen, Jen-Chuen Hsieh, Tung-Ping Su, and Li-Fen Chen* (2010) Distinct neuronal oscillatory responses between patients with bipolar and unipolar disorders: a magnetoencephalographic study. Journal of Affective Disorders, 123:270-275.
  • Jia-Xiu Liu, Yong-Sheng Chen, and Li-Fen Chen* (2010) Fast and accurate registration techniques for affine and nonrigid alignment of MR brain images. Annals of Biomedical Engineering, 38(1):138-157

2009

  • Jia-Xiu Liu, Yong-Sheng Chen, and Li-Fen Chen* (2009) Accurate and robust extraction of brain regions using a deformable model based on radial basis functions. Journal of Neuroscience Methods, 183(2):255–26.
  • Ren-Jen Hwang, Chi-Hsun Wu, Li-Fen Chen, Tzu-Chen Yeh, Jen-Chuen Hsieh*. (2009) Female menstrual phases modulate human prefrontal asymmetry: a magnetoencephalographic study. Hormones and Behavior, 55:203-209.
  • Lynn Y.L. Shih, Li-Fen Chen, Wen-Jui Kuo, Tzu-Chen Yeh, Yu-Te Wu, Ovid J.L. Tzeng, Jen-Chuen Hsieh*. (2009) Sensory acquisition in the cerebellum: An fMRI study of cerebrocerebellar interaction during visual duration discrimination. Cerebellum, 8(2):116-126.

2008

  • Shyan-Shiou Chen, Pei-Chi Tu, Tung-Ping Su, Jen-Chuen Hsieh, Ying-Chia Lin, Li-Fen Chen* (2008) Impaired frontal synchronization of spontaneous magnetoencephalographic activity in patients with bipolar disorder. Neuroscience Letters, 445(2):174-178.
  • Jia-Xiu Liu, Yong-Sheng Chen, and Li-Fen Chen* (2008) Nonlinear registration based on the approximation of radial basis function coefficients. Journal of Medical and Biological Engineering, 28(3): 119-126.
  • Yong-Sheng Chen, Li-Fen Chen*, Ya-Ting Chang, Yung-Tien Huang, Tong-Ping Su, Jen-Chuen Hsieh (2008) Quantitative evaluation of brain magnetic resonance images based on voxel-based morphometry and bayesian theorem for patients with bipolar disorder. Journal of Medical and Biological Engineering, 28(3): 127-133.
  • Ren-Jen Hwang, Li-Fen Chen, Tzu-Chen Yeh, Pei-Chi Tu, Chung-Haow Tu, Jen-Chuen Hsieh* (2008) The resting frontal alpha asymmetry across the menstrual cycle: a magnetoencephalographic study. Hormones and Behavior, 54:28–33.

2007

  • Shyan-Shiou Chen, Li-Fen Chen, Yu-Te Wu, Yu-Zu Wu, Po-Lei Lee, Tzu-Chen Yeh, and Jen-Chuen Hsieh* (2007) Detection of synchronization between chaotic signals: an Adaptive Similarity Approach. Physical Review E, 76:066201-1~11.

2006

  • Yong-Sheng Chen, Chih-Yu Cheng, Jen-Chuen Hsieh, and Li-Fen Chen* (2006) Maximum contrast beamformer for electromagnetic mapping of brain activity. IEEE Transactions on Biomedical Engineering, 53(9):1765-1774.
  • Lieber Po-Hung Li, An-Suey Shiao, Li-Fen Chen, David M. Niddam, Shyue-Yih Chang, Chiang-Fen Lien, S. K. Lee, and Jen-Chuen Hsieh* (2006) Healthy-side dominance of middle- and long-latency neuromagnetic fields in idiopathic sudden sensorineural hearing loss. European Journal of Neuroscience, P1–10.
  • Yu-Zu Wu, David M. Niddam, Chun-Chuan Chen, Kwong-Kum Liao, Chou-Ming Cheng, Li-Fen Chen, Po-Lei Lee, Shyan-Shiou Chen, Tzu-ChenYeh, and Jen-Chuen Hsieh* (2006) Effects of cognitive demands on postmovement motor cortical deactivation. NeuroReport, 17(4):371-375.

2005

  • Chih-I Hung, Po-Lei Lee, Yu-Te Wu*, Li-Fen Chen, Tzu-Chen Yeh, Jen-Chuen Hsieh (2005) Recognition of motor imagery electroencephalography using independent component analysis and machine classifiers. Annals of Biomedical Engineering, 33(8):1053-1070.
  • Yung-Cheng Cheng, Yong-Sheng Chen, Jen-Chuen Hsieh, Li-Fen Chen* (2005) Camera-guided coordinate system alignment for neuromagnetic source estimation. International Journal of Bioelectromagnetism, 7(2):86-89.
  • Hong-Yi Liu, Yong-Sheng Chen*, Li-Fen Chen, and Jen-Chuen Hsieh (2005) Statistical mapping of cortical activities using minimum-variance maximum-discrimination spatial filtering. International Journal of Bioelectromagnetism, 7(2):104-107. [Non-SCI]
  • David M. Niddam, Li-Fen Chen, Yu-Te Wu, Jen-Chuen Hsieh* (2005) Spatiotemporal brain dynamics in response to muscle stimulation. NeuroImage, 25(3):942-951.

2004

  • Ching-Liang Lu, Yu-Te Wu, Tzu-Chen Yeh, Li-Fen Chen, Full-Young Chang, Shou-Dong Lee, Low-Tone Ho, Jen-Chuen Hsieh* (2004) Neuronal correlates of gastric pain induced by fundus distension: a 3T-fMRI study. Neurogastroenterology and Motility, 16(5):575-587.
  • Wen-Jui Kuo, Tzu-Chen Yeh, Jun-Ren Lee, Li-Fen Chen, Po-Lei Lee, S-S Chen, Low-Tone Ho, Daisy L. Hung, Ovid J.-L Tzeng, Jen-Chuen Hsieh* (2004) Orthographic and phonological processing of Chinese characters: an fMRI study. NeuroImage. 21:1721-1731.

2003

  • Po-Lei Lee, Yu-Te Wu, Li-Fen Chen, Yong-Sheng Chen, Chou-Ming Cheng, Tzu-Chen Yeh, Low-Tone Ho, Mau-Song Chang, Jen-Chuen Hsieh* (2003) ICA-based spatiotemporal approach for single-trial analysis of postmovement MEG beta synchronization. NeuroImage, 20:2010-2030.
  • Lieber Po-Hung Li, An-Suey Shiao, Yung-Yang Lin, Li-Fen Chen, David M. Niddam, Shyue-Yih Chang, Chiang-Fen Lien, Nan-San Chou, Low-Tone Ho, Jen-Chuen Hsieh* (2003) Healthy-side dominance of cortical neuromagnetic responses in sudden hearing loss. Annals of Neurology, 53:810-815.
  • Yu-Te Wu*, Li-Fen Chen, Hui-Yun Chen, Po-Lei Lee, Tzu-Chen Yeh, Jen-Chuen Hsieh (2003) A wavelet-based approach for color image registration. Journal of Imaging Science and Technology. 47(3):185-199.
  • Yu-Te Wu*, Li-Fen Chen, Po-Lei Lee, Tzu-Chen Yeh, Jen-Chuen Hsieh (2003) Discrete signal matching using coarse-to-fine wavelet basis functions. Pattern Recognition 36: 171-192.

2002

  • Yu-Te Wu*, Hui-Yun Chen, Li-Fen Chen, Po-Lei Lee, Tzu-Chen Yeh, Jen-Chuen Hsieh (2002) Fetal heart tracking in ultrasound image sequences using coarse-to-fine wavelet. Journal of Medical and Biological Engineering, 22(2): 67-74.
  • Po-Lei Lee, Li-Fen Chen, Yu-Te Wu*, Hsiu-Feng Chiu, Kuo-Kai Shyu, Tzu-Chen Yeh, Jen-Chuen Hsieh (2002) Classifying MEG 20Hz rhythmic signals of left, right index finger movement and resting state using cascaded radial basis function networks.Journal of Medical and Biological Engineering 22(3): 147-152.
  • Li-Fen Chen, Hong-Yuan Mark Liao, and Ja-Chen Lin (2002) Wavelet-based optical flow estimation. IEEE Transactions on Circuits and Systems for Video Technology 12(1): 1-12.

2001

  • Li-Fen Chen, Hong-Yuan Mark Liao*, Chin-Chuan Han and Ja-Chen Lin (2001) Why recognition in a statistics-based face recognition system should be based on the pure face portion: a probabilistic decision-based proof. Pattern Recognition 34(7): 19-29.

2000

  • Li-Fen Chen, Hong-Yuan Mark Liao*, Ja-Chen Lin, Ming-Tat Ko and Gwo-Jong Yu (2000) A new LDA-based face recognition system which can solve the small sample size problem. Pattern Recognition 33(10): 1713-1726.